Designing Scalable Purification Strategies That Preserve RNA Integrity Across Increasingly Complex RNA Constructs
1:30 pm - Thursday 18th February 2027
- Implementing chromatography, tangential flow filtration & affinity-based methods for high-purity circRNA
- Addressing challenges in removing double-stranded RNA to meet regulatory specifications & reduce immunogenicity
- Optimising purification processes to maximise yield whilst achieving target purity levels
- Overcoming bottlenecks in downstream processing when transitioning from research to GMP scale
