Optimising Peptide-Based Nanoparticles for Functional RNA Delivery to Enable Therapeutic Gene Modulation & Protein Replacement
9:30 am - Thursday 18th February 2027
- Leveraging AI-driven peptide optimisation to design cell-specific targeting motifs and formulate peptide-based nanoparticles without antibody conjugation or additional surface modifications
- Improving targeting specificity and reducing off-target delivery through optimised peptide-based formulations, while supporting repeat dosing for therapeutic applications
- Demonstrating the versatility of peptide-based delivery through in vivo data on T-cell modification for CAR-T applications and protein replacement across tumour models
